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[Epidemiological characteristics of confirmed COVID-19 cases in Tianjin].

Identifieur interne : 000061 ( an2020/Analysis ); précédent : 000060; suivant : 000062

[Epidemiological characteristics of confirmed COVID-19 cases in Tianjin].

Auteurs : X C Dong [République populaire de Chine] ; J M Li [République populaire de Chine] ; J Y Bai [République populaire de Chine] ; Z Q Liu [République populaire de Chine] ; P H Zhou [République populaire de Chine] ; L. Gao [République populaire de Chine] ; X Y Li [République populaire de Chine] ; Y. Zhang [République populaire de Chine]

Source :

RBID : pubmed:32164400

Abstract

Objective: To investigate the clinical and epidemiological characteristics of 135 confirmed cases of COVID-19 in Tianjin. Methods: The clinical and epidemiological data of 135 cases of COVID-19 in Tianjin were collected, and the data were analyzed with descriptive method. The factors influencing the severity of the illness were analyzed. Results: Among the 135 COVID-19 cases, 72 were males and 63 were females, the age of the cases was (48.62±16.83) years, and the case fatality rate was 2.22%. Local transmission caused 74.81% of the cases. A total of 33 clusters occurred, involving 85.92% of all COVID-19 cases. The median of the incubation period of COVID-19 was 6.50 days, the average generation interval was 5 days, and the household secondary transmission rate was 20.46%. Fever was the main symptom (78.63%), followed by cough (56.48%). Multivariate regression analysis indicated that age (OR=1.038, 95%CI: 1.010-1.167) and the number of chronic underlying diseases (OR=1.709, 95%CI: 1.052-2.777) were the risk factors of severe illness. Conclusions: Fever was the main symptom at the early phase of COVID-19 in Tianjin, and the local cluster cases accounted for high proportion in confirmed COVID-19 cases reported in Tianjin. Severe illness was prone to occur in people with old age and multi underlying diseases. Strict isolation of close contacts and intensive care of high-risk groups are the main measures to reduce the morbidity and case fatality of COVID-19.

DOI: 10.3760/cma.j.cn112338-20200221-00146
PubMed: 32164400


Affiliations:


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<div type="abstract" xml:lang="en">
<b>Objective:</b>
To investigate the clinical and epidemiological characteristics of 135 confirmed cases of COVID-19 in Tianjin.
<b>Methods:</b>
The clinical and epidemiological data of 135 cases of COVID-19 in Tianjin were collected, and the data were analyzed with descriptive method. The factors influencing the severity of the illness were analyzed.
<b>Results:</b>
Among the 135 COVID-19 cases, 72 were males and 63 were females, the age of the cases was (48.62±16.83) years, and the case fatality rate was 2.22%. Local transmission caused 74.81% of the cases. A total of 33 clusters occurred, involving 85.92% of all COVID-19 cases. The median of the incubation period of COVID-19 was 6.50 days, the average generation interval was 5 days, and the household secondary transmission rate was 20.46%. Fever was the main symptom (78.63%), followed by cough (56.48%). Multivariate regression analysis indicated that age (
<i>OR</i>
=1.038, 95%
<i>CI</i>
: 1.010-1.167) and the number of chronic underlying diseases (
<i>OR</i>
=1.709, 95%
<i>CI</i>
: 1.052-2.777) were the risk factors of severe illness.
<b>Conclusions:</b>
Fever was the main symptom at the early phase of COVID-19 in Tianjin, and the local cluster cases accounted for high proportion in confirmed COVID-19 cases reported in Tianjin. Severe illness was prone to occur in people with old age and multi underlying diseases. Strict isolation of close contacts and intensive care of high-risk groups are the main measures to reduce the morbidity and case fatality of COVID-19.</div>
</front>
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